Microbiology Lab Services

Direct Colony Species Identification Fungal/Bacterial


Our philosophy here is, we need to stay on the cutting edge of technology. And we've realized that molecular is not only now the future, but it will continue to be the future."

James Snyder, Ph. D.
Professor of Pathology & Laboratory Medicine
University of Louisville Hospital


Identification and Speciation from Culture

MicroKEY Test Options


AFB Panel - Non tuberculosis Mycobacterium Identification

Bacteria:
Mycobacterium spp, Mycobacterium avium complex (Mycobacterium avium and Mycobacterium intercellulare) Mycobacterium abscessus group (Mycobacterium abscessus and Mycobacterium massiliensis) identification along with these related species: Nocardia, Rhodococcus, Gordona, Tsukamurella, Streptomyces, and Actinomyces.

Resistance Genes:
Aminoglycoside resistance and Macrolide resistance.

Cultured Bacteria Identification

Bacteria:

Next Gen Comprehensive DNA Sequencing for detection of bacteria and qPCR rapid screening for resistance genes, including methicillin, vancomycin, beta lactam, carbapenem, macrolide, aminoglycoside, tetracycline, quinolone, bactrim, and extended spectrum beta lactamase.

Cultured Yeast and Mold Identification

Fungi:
Next Gen Comprehensive DNA Sequencing for detection of fungi, yeast and molds and qPCR rapid screening for Candida albicans and Trichophyton rubrum.

Bacteria & Fungi NGS Can Identify


Bacteria  Fungi 
Bacteria NamePAFBAFBYeastsMolds
S. aureus
E. coli
P. aeruginosa
E. faecalis
Etc.
Nocardia
Actinomyces
Streptomyces
Etc.
M. tuberculosis
M. avium cpx
M. abscessus
Etc.
C. albicans
C. glabrata
C. auris
Cryptococcus
Etc.
Aspergillus
Fusarium
Penicillium
Etc.
Includes multiple genera and speciesIncludes multiple genera and speciesAFB only includes Mycobacteria
Includes multiple genera and speciesIncludes multiple genera and species

When to use MicroGenDX


Microbial identification to the species level using NGS


College of American Pathology Proficiency Results, 2009 – 2018

Species PanelTest FrequencyNumber of Blinded Samples per TestNumber of Blinded SpecimensProficiency Score
IDR3 Times per year for 5 years57597.3%
MRS-5 (M)3 Times per year for 10 years5150100.0%
F13 Times per year for 10 years515098.0%
D83 Times per year for 10 years515099.3%
VRE3 Times per year for 10 years240100.0%
GIP3 Times per year for 2 years530100.0%
HC-63 Times per year for 1 year515100.0%
TVAG3 Times per year for 1 year39100.0%
Alternate3 Times per year for 10 years6180100.0%
Blinded Specimens Total 799Mean Accuracy Rate 99.4%
parallax background

Global Leader In Molecular Diagnostics


PCR +
NEXT GENERATION
DNA SEQUENCING


AND OUR OWN PROPRIETARY CURATED DATABASE OF

50,000

MICROBIAL SPECIES SEQUENCING CODES


17

RESISTANCE GENES


  • Beta-lactam:
    1. TEM and 2. SHV
  • Carbapenem:
    3. NDM, 4. KPC, and 5. OXA-48
  • Macrolide:
    6. ermB
  • Aminoglycoside:
    7. aacC6-aph3 and
    8. ant-la – aph2
  • Tetracycline:
    9. tetM and 10. tetB
  • Quinolone:
    11. qnr and 12. gyrA
  • Vancomycin:
    13. vanA
  • Methicillin:
    14. mecA
  • Bactrim:
    15. Sul I and 16. Sul II
  • Extended Spectrum Beta Lactamase:
    17. CTX-M

NGS RESULTS IN 3-5 DAYS


Our success: Medical diagnostics and beyond

MicroGenDX is a trusted partner for leading research scientists in government and industry

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