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October 1, 2021
microgendx qpcr ngs faster for infectious disease

MicroGenDX’s qPCR+NGS Provides Faster, Life-Saving Infectious Disease Diagnoses

Next-Generation Sequencing (NGS) can be used to diagnose infectious diseases more rapidly and more accurately than traditional methods such as cultures, gram staining, and other biochemical and molecular tests that are organism-specific. In one reported case, NGS correctly identified the infectious organism after nearly 40 different diagnostic tests on 10 sample types. In another scenario, in cases of sepsis, timely targeted treatment with rapid identification of the microbial pathogen can be lifesaving. Instead of delaying diagnosis by ordering and waiting for organism-specific microbiology identification and susceptibility results, MicroGenDX’s qPCR+NGS can identify the bacterial, viral, or fungal source of infection and […]
September 21, 2021
Genomic Surveillance

Genomic Surveillance Is Essential In The Battle Against COVID-19

Thanks to advances in sequencing technologies, the complete genome of the SARS-CoV-2 (COVID-19) virus was determined rapidly at the outset of the pandemic. This has proven essential in understanding how SARS-CoV-2 infects humans and causes disease. The SARS-CoV-2 genome contains genetic information for the production of viral spike protein (S protein), which is needed for the virus to attach to and infect human cells. Each viral particle is covered by numerous S proteins, allowing it to bind to a unique protein receptor found on cells in the body. Genomic surveillance — the identification, tracking and monitoring of SARS-CoV-2 variants — […]
May 25, 2021
urology uti

MicroGenDX Next-Generation Sequencing: The Next Frontier in Diagnosing and Treating Urologic Diseases

Urinary Tract Infections (UTIs) continue to pose a substantial healthcare burden worldwide and remain to be one of the most frequent infections seen globally. In the U.S., both adult male and female UTIs account for the most clinic visits every year. According to data gathered by the NIH, around 7 million annual clinic visits were due to UTIs, and there were more than 1 million UTI cases among children. UTIs also accounted for about 1 million urgent care visits and 100,000 hospitalization cases every year. Because UTIs are often treated empirically — where patients are often prescribed antibiotics without a […]
May 14, 2021
MicroGenDX lab techs

It is Time to Modernize Standard Hospital Testing with Next-Generation Sequencing

Next-generation sequencing is more effective, efficient, and designed to put patient well-being first compared to microbiology cultures. In healthcare, efficacy and speed are cardinal factors determining courses of analysis, diagnosis, and treatment. However, infectious disease diagnostics, microbiological culture technology — a method dating back 160 years— is still the standard method for determining types and quantities of organisms. However, next-generation sequencing (NGS) is a newer and more accurate method employed by MicroGenDX to generate accurate life-changing — and often life-saving — results in a short timeframe to better suit patient outcomes. Originating from advancements in DNA sequencing, MicroGenDX NGS takes […]
April 30, 2021

Next-Generation Sequencing Helps Clinicians Win the War Against Biofilm Infections

Chronic infection and chronic non-healing wounds are devastating to the patient, a challenge to the healthcare provider, and costly to the healthcare system. Quite often, the culprit is biofilm. Biofilm is a thin coating consisting of bacteria embedded in a moist, adhesive matrix covering living tissues and indwelling medical devices like catheters, stents, pacemakers, and prosthetics. This matrix protects the organism, making it resistant to phagocytosis by white blood cells and killing by antibiotics. Biofilms are a huge medical problem because they make bacterial infections extremely difficult to diagnose and treat. Biofilm and Antibiotic Tolerance/Resistance According to a study in […]
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