Biofilm infections have increasingly come into prominence in the past three decades. Acute Infections are bacterial diseases that are caused by planktonic bacterial cells ( Single Cell ) Chronic infections are caused by Biofilms, multiple microbial species with altered phenotype encased in a protective EPS matrix. Biofilms can form on any surface in the human body.
CDC/ NIH research shows that 60-80% of chronic infections are caused by Bio-Films. Cultures fail to identify the microorganisms in a biofilm phenotype. Microbial DNA sequencing can accurately detect the microorganisms in a biofilm."