MicroGenDX Published Studies

March 4, 2019

Determining the utility of standard hospital microbiology testing: Comparing standard microbiology cultures with DNA sequence analysis in patients with chronic sinusitis

Results: Specimens were obtained from 29 female and 16 male patients with a mean age of 50 years. A total of 45 cultures were included in our final analysis; five cultures were excluded after inappropriate laboratory processing. Results from these patients were compared and analyzed. Cohen’s weighted kappa analysis showed agreement between the two testing

Sarah K. Rapoport, Alyssa J. Smith, Maxwell Bergman, Kelly A. Scriven, Itzhak Brook, Suzette K. Mikula

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March 4, 2019

General Assembly, Diagnosis, Pathogen Isolation: Proceedings of International Consensus on Orthopedic Infections

shown to be powerful tools in detecting prosthetic joint infections (PJIs) with negative cultures, although conflicting data exist on PCR. Sonication of explanted prosthetics can enhance both the sensitivity of conventional cultures and PCR.

Level of Evidence: Strong

Delegate Vote: Agree: 85%, Disagree: 9%, Abstain: 6% (Super Majority, Strong Consensus)

Pablo S. Corona, Karan Goswami, Naomi Kobayashi, William Li, Adolfo Llinas Volpe, Oliver Marín-Pe~na, Daniel Monsalvo, Fernando Motta, Alexander Shope, Majd Tarabichi, Matias Vicente, Hamidreza Yazdi

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January 18, 2019
PCR analysis of Sinusitus Dr Song 2019

Use of Dipstick Assay and Rapid PCR-DNA Analysis of Nasal Secretions for Diagnosis of Bacterial Sinusitis in Children With Chronic Cough

Background: Chronic cough in children is a diagnostic challenge.

Objective: To discover the utility of nasal dipsticks and polymerase chain reaction (PCR)-DNA analysis in differentiating bacterial sinusitis from other causes of chronic cough and identifying pathogens from the nasal cavity.

Charles Song, MD, Jeena Chorath, MD, Youngju Pak, PhD, and Nasser Redjal, MD

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July 17, 2018
McDonald_NGS_PhaseIITrial_RIU_2017-1

Comparative Phase II Study of Standard Urine C&S vs DNA NGS Testing for UTIs

Many studies have discussed clinical practice guidelines for the treatment of cystitis and pyelonephritis. Treatment of uncomplicated urinary tract infections (UTIs) can be based on empiric antibiotic therapy.

Michael McDonald, MD, Darian Kameh, MD, Mark E. Johnson, PhD, Truls E. Bjerklund Johansen, MD, DMSci, David Albala, MD, Vladimir Mouraviev, MD, PhD

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