May 10, 2017

“You can identify it, you treat it, now you’re able to better heal it.” Matthew Regulski, DPM

Dr. Matthew Regulski was kind enough to sit down and discus his experience with MicroGen DX*. Dr. Matthew Regulski can be found at Ocean County Foot and Ankle Surgical Associates in Toms River New Jersey (contact information below). “I run all the clinical research, wound healing program that we do here,” Dr. Regulski told us. “Mainly do a lot of limb salvage, diabetic foot reconstruction, wound healing. Been doing it for 12 years.”

We asked Dr. Regulski to recall his first impressions when he heard about what MicroGen DX could do for his patients. “When somebody comes to you and says, “This is the greatest thing ever”, this will do everything for your patient. You need to be skeptical about that.

“The initial thoughts were I thought it was neat that we are using DNA finally to do that. I

May 17, 2017

The MicroGen DX Laboratory: Next-Gen Sequencing; Superior Diagnostics Simplified


More than 50 million Americans suffer from infections every year, including Wound, Nail, Urinary, Joint and Sinus Infections. Research has shown infections that are not cleared can move to a biofilm phenotype creating a barrier to healing and lead to a chronic infection disease state.

These chronic infections are not caused by “single pathogens” but rather “Biofilms” or “Collaborative Communities” of multiple species of bacteria and fungi.

We now know there are over 50,000 species of microbes and 99% of them can not be identified using the traditional culture method.

Next Generation DNA Sequencing is the gold standard in delivering precise data in other areas of medicine, and now we are making this technology available to physicians for the diagnosis of Infections with accurate microbial identification.

May 18, 2017

“This is a huge change where we can diagnose these patients earlier.” An interview with Michael McDonald, MD

Doctor Michael McDonald sat down with us recently to share his experience evaluating Next Generation DNA sequencing when compared to traditional cultures. Dr. McDonald is a urologist, board certified at Florida Hospital Celebration in Florida. He is associate professor of Urology at University of Central Florida.

“When we were first introduced to the Next-Gen Sequencing,” Dr. McDonald told us, “we thought we need some criteria to evaluate its efficacy of diagnosis in the realm of urinary tract infections and other opportunities. I wanted to look at a head to head study, comparing Next-Gen Sequencing and urine cultures for patients with UTI symptoms. Specifically those patients that have Dysuria, Urinary Frequency, Urgency, Hematuria, those patients that have recurrent UTI symptoms and those that have resistant treatment of UTIs.” 

June 27, 2017

Identifying the causative microbes of infections with Next-Gen Sequencing- Andrew Pugliese M.D.


Infectious Disease doctor Andrew Pugliese, M.D. is a pioneer in the non-surgical treatment of acute and chronic sinusitis.  He has been practicing medicine for more than 20 years and is triple board certified in infectious disease, sleep and internal medicine. He recently sat down to share with us some of his experience in using next Generation DNA sequencing in the care of his patients. Specifically, Dr. Pugliese explained how the ability to identify multiple different species of pathogen is vital to the care of certain wounds, especially when the infection has developed into a biofilm state.

“I had heard about biofilm,” Dr. Pugliese told us, “but really didn’t understand just how complex biofilm was and that how the multiple organisms involved in the biofilm formation could really have a negative impact on my treatment of these chronic infections.”…

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