MicroGenDX Published Studies

January 18, 2019

Use of Dipstick Assay and Rapid PCR-DNA Analysis of Nasal Secretions for Diagnosis of Bacterial Sinusitis in Children With Chronic Cough

Aims

The diagnosis of periprosthetic joint infection can be difficult due to the high rate of culturenegative infections. The aim of this study was to assess the use of next-generation sequencing for detecting organisms in synovial fluid.

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March 4, 2019

General Assembly, Diagnosis, Pathogen Isolation: Proceedings of International Consensus on Orthopedic Infections

shown to be powerful tools in detecting prosthetic joint infections (PJIs) with negative cultures, although conflicting data exist on PCR. Sonication of explanted prosthetics can enhance both the sensitivity of conventional cultures and PCR.

Level of Evidence: Strong

Delegate Vote: Agree: 85%, Disagree: 9%, Abstain: 6% (Super Majority, Strong Consensus)

Pablo S. Corona, Karan Goswami, Naomi Kobayashi, William Li, Adolfo Llinas Volpe, Oliver Marín-Pe~na, Daniel Monsalvo, Fernando Motta, Alexander Shope, Majd Tarabichi, Matias Vicente, Hamidreza Yazdi

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March 4, 2019

Determining the utility of standard hospital microbiology testing: Comparing standard microbiology cultures with DNA sequence analysis in patients with chronic sinusitis

Results: Specimens were obtained from 29 female and 16 male patients with a mean age of 50 years. A total of 45 cultures were included in our final analysis; five cultures were excluded after inappropriate laboratory processing. Results from these patients were compared and analyzed. Cohen’s weighted kappa analysis showed agreement between the two testing

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April 16, 2019

Metagenomics in diagnosis and improved targeted treatment of UTI

Results: This paper is derived from an extensive review and analysis of the available literature on the topic of metagenomic sequencing in urological science, using the PubMed search engine. The search yielded a total of 406 results, and manual selection of appropriate papers was subsequently performed.

Matthew Dixon · Maria Stefil · Michael McDonald · Truls Erik Bjerklund‑Johansen · Kurt Naber · Florian Wagenlehner · Vladimir Mouraviev

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