shown to be powerful tools in detecting prosthetic joint infections (PJIs) with negative cultures, although conflicting data exist on PCR. Sonication of explanted prosthetics can enhance both the sensitivity of conventional cultures and PCR.
Level of Evidence: Strong
Delegate Vote: Agree: 85%, Disagree: 9%, Abstain: 6% (Super Majority, Strong Consensus)
Pablo S. Corona, Karan Goswami, Naomi Kobayashi, William Li, Adolfo Llinas Volpe, Oliver Marín-Pe~na, Daniel Monsalvo, Fernando Motta, Alexander Shope, Majd Tarabichi, Matias Vicente, Hamidreza Yazdi
Results: Specimens were obtained from 29 female and 16 male patients with a mean age of 50 years. A total of 45 cultures were included in our final analysis; five cultures were excluded after inappropriate laboratory processing. Results from these patients were compared and analyzed. Cohen’s weighted kappa analysis showed agreement between the two testing
Results: This paper is derived from an extensive review and analysis of the available literature on the topic of metagenomic sequencing in urological science, using the PubMed search engine. The search yielded a total of 406 results, and manual selection of appropriate papers was subsequently performed.
Matthew Dixon · Maria Stefil · Michael McDonald · Truls Erik Bjerklund‑Johansen · Kurt Naber · Florian Wagenlehner · Vladimir Mouraviev