Latest Posts
January 27, 2026
DON’T PANIC The Clinician’s Guide to the Genomic Galaxy is designed to help you navigate the genomic landscape that is materializing beneath your feet as we speak. It is materializing quickly; we should learn to walk now so that we may run in the days ahead. When clinicians first encounter next-generation sequencing (NGS), or hear it discussed at conferences, the road is difficult to see through all the caution signs and while caution is certainly appropriate, these signs are often treated like “road closed” signs. Some of the cautionary statements that frequent discussions of molecular diagnostics are: NGS is too […]
January 23, 2026
A Structural Shift in Outpatient Orthopedics – and the Role of Diagnostics Beginning January 1, 2026, a fundamental shift will take place in outpatient orthopedic care. The Centers for Medicare & Medicaid Services (CMS) has finalized a rule expanding Ambulatory Surgical Center (ASC) eligibility to include select revision total knee and hip arthroplasty procedures. This decision moves some of the most complex orthopedic cases into outpatient settings for appropriately selected patients. While this policy change expands access and efficiency, it also raises the bar for diagnostic certainty. Revision arthroplasty carries inherently higher clinical risk-particularly related to occult infection-and the ASC environment allows far less tolerance for […]
December 30, 2025
A Critical Issue Affecting Millions of Women Intrauterine devices represent one of the most effective forms of long-acting reversible contraception available today, with efficacy rates comparable to sterilization methods. Yet despite their clinical advantages, a staggering 57% of IUD patients in the United States choose to have their devices removed before the recommended duration of use. This represents not just a contraceptive failure, but a missed opportunity to provide sustained, reliable reproductive health management to millions of women. For clinicians managing IUD patients, these premature removals translate into valuable clinical time spent addressing complications, counseling disappointed patients, and navigating alternative […]
December 3, 2025
Periprosthetic joint infections (PJI) remain one of the most serious and costly complications associated with total joint arthroplasty. Although they occur in 1–2% of cases, the consequences are severe—ranging from multiple revision surgeries and prolonged hospital stays to reduced patient mobility and increased mortality risk. Beyond clinical outcomes, the financial burden is substantial, with average cost of $100,000 per episode and lifetime costs reaching roughly $391,000 per patient. A particularly complex clinical challenge arises when PJIs are culture-negative, which occurs in an estimated 15–30% of cases. When standard microbiological cultures fail to identify a culprit pathogen, orthopedic surgeons and infectious […]
September 24, 2025
In neurologic infection cases, time determines patient outcomes. Delays in identifying the cause of infection can lead to extended ICU stays, major complications, or diminished quality of life for patients. Traditional culture methods can take days and sometimes weeks to yield results—time that neither physicians or their patients have. Our integration of the Illumina MiSeq i100 Plus enables delivery of Next-Gen DNA Sequencing (NGS) results as soon as 24 hours after sample receipt. This advancement is providing neurologists and infectious disease specialists with insights when they need them most, reducing diagnostic delays. By minimizing the time lag between testing and […]