March 4, 2026
A Paradigm Shift in Urology For much of modern medicine, a foundational assumption shaped the way clinicians approached urinary tract health: healthy urine is sterile. That assumption influenced how specimens were cultured, how infections were diagnosed, and how treatment decisions were made. It also meant that any bacterium detected in urine was presumed to be either a contaminant or a pathogen- with little consideration for a middle ground. Over the past decade, advances in molecular sequencing have dismantled this paradigm. Culture-independent techniques, particularly 16S ribosomal RNA (rRNA) gene sequencing, have revealed that the human urinary tract harbors a resident […]
April 15, 2025
MicroGen Diagnostics said last week that it has inked a partnership with German medical laboratory Labor Dr. Fenner and Colleagues to offer rapid microbial DNA sequencing services to European customers.
August 3, 2022
MicroGen Diagnostics is growing its business for targeted sequencing-based orthopedic and urological infection detection on the heels of new contracts and outcomes studies…. the JBJS study showed the MicroGen test detected polymicrobial infections in a majority of cases that had shown no organism growth after standard microbial culture. Karan Goswami, first author on the JBJS study and a researcher at the Rothman Orthopaedic Institute in Philadelphia, said in an email that work marks “the largest cohort reporting the utility of NGS in isolating infective organisms in culture-negative cases.”
April 21, 2022
URINARY TRACT INFECTIONS (UTIs) are a common outpatient infection, especially in women aged over 65 years. At least 1 in 2 women will have a UTI in her lifetime. In all, 20% to 40% of these women will have 1 recurrence, and, of those, up to 50% will go on to have multiple recurrences.1,2 The gold-standard diagnostic tool for UTI is urine culture, a technology that relies upon the ability of the causative organism(s) to grow in artificial conditions. The problem with culture is that many organisms that cause symptomatic urinary tract infections will not grow on standard culture medium, […]
January 4, 2022
As COVID-19 cases continue to spike throughout the Roaring Fork Valley since the omicron variant made its presence known in mid-December….the Free COVID-19 Testing Roaring Fork Valley has announced that it will soon offer same-day results on all testing. “The service, in collaboration with MicroGenDX — a company specializing in low-cost, FDA-authorized, highly accurate qPCR + NGS microbial diagnostics — has set up a local lab processing center in Carbondale….the announcement explained.”