Next-Gen DNA Sequencing for Precise Microbial Diagnosis of Periodontal Infections
Why you should choose PerioDX Next Generation Sequencing (NGS) for your patients with Periodontal Disease.
- PCR is inadequate to diagnose as needed. Current saliva testing for Periodontal disease, is limited to microbes in the panel tested. Disease-causing microbes can easily be missed using PCR alone. NGS is the most-advanced technology available for the Identification of microbes in disease, and for monitoring the progression in levels of microbes during a treatment plan.
- PerioDX offers superior sampling method that offers you the flexibility to test saliva, periodontal pockets, or combine both samples for a comprehensive test result.
- Biofilms have a major impact on Periodontal disease. Only PerioDX using Next Generation Sequencing can identify the organisms contributing to biofilm formation and persistence.
Benefits of Next-Gen Sequencing vs PCR
PCR is an excellent diagnostic tool for rapid & specific species detection. PCR panels can detect between 8-35 species of microbes.
Next-Gen DNA Sequencing is the best option for filling in the gap between rapid PCR detection and identifying all the species present in an infection.
MicroGenDX has identified over 6,500 microbes in human samples through Next-Gen Sequencing. Many times identifying dominant microbial species missed by PCR panels.
| PCR | Next-Gen DNA Sequencing |
|---|---|
| Rapid Turn Around Time | Detects all Microbes including Aerobes, Anaerobes, Facultative anaerobes and Fungal Species |
| Limited panel detects 8-35 of the most common species of microbes | Can identify 50,000+ microbes with 99.9% accurate detection |
| May NOT detect species if mutated | Identifies all microbes by percentage of the unique DNA found in the sample |
| Could miss dominant species within the infection | 6,500+ microbes identified in human tests to date |
ABOUT OUR TEST:
You can choose Saliva, or Saliva-Plus pocket sampling. In addition to saliva, we can process samples from deep in periodontal pockets. This will give you a more comprehensive diagnostic result versus saliva alone. Combine both collection methods in one bio-hazard bag and this will be run as one test.
Answers to commonly asked questions:
Please complete as shown here:
Log into the lab portal at https://microgendxlabs.com/Account/Login to receive your results in 3-5 days.
You may access your results by registering for a Lab Portal (MicroGenDXLabs.com) account. Click Here to Sign Up for Portal Access. Once your Lab Portal account has been approved, you can use your log in and password to access your patient’s results.
See Set-Up Process Below
MicroGendx laboratory:
Is the world leader in Next Generation DNA Sequencing in the field of microbial identification. MicroGenDX has processed over 350,000 human samples for thousands of physicians across the country.
We’re confident our multi-level solution combining the best in PCR and Next-Gen DNA Sequencing is the KEY to improving patient care.